The defending champion of the tournament in Melbourne defeated the 114th player in the world, Russian Aslan Karatsev, 6: 3, 6: 4, 6: 2, without major problems after 113 minutes of the game.
It was the 20th consecutive victory of the World No. 1 at the tournament in Melbourne Park, which brought him a place in the 28th Grand Slam final in his career.
Grigor Dimitrov caused a big upset on Sunday by sweeping past last year's finalist Dominic Thiem for a place in his fourth Australian Open quarter-final.
Dimitrov, the No. 18 seed, played with great athleticism beat third seed Thiem, who was noticeably low on energy, 6-4, 6-4, 6-0 in just over two hours on Rod Laver Arena.