Turkish Airlines has inaugurated flights to San Francisco, the national flag carrier said in a statement.
It is the airline's second Californian destination, and its 11th in the Americas. The airline already has services to Buenos Aires, Sao Paulo, Toronto, Chicago, Houston, Los Angeles, New York, Washington, Boston and Montreal.
During a two-day official visit to neighbouring Moldova, Romania's new President, Klaus Iohannis, said Romania remains an "anchor of stability in the region" as well as a "partner of neighbouring Moldova and Ukraine on their path to Europe".
Moldova's parliament on Thursday voted down the government proposed by Prime Minister Iurie Leanca, more than two months after general elections gave a narrow victory to pro-European Union parties.
The United States on Feb. 10 denied that it was coordinating air strikes either directly or indirectly with the Syrian regime against Islamic militants and renewed calls for President Bashar al-Assad to go.
In an interview with the BBC, Assad said Damascus was being informed about the US-led coalition air strikes against the Islamic State of Iraq and the Levant (ISIL).
Romanian analysts have expressed concerns that Moldova's chances for future integration into the European Union are diminishing after the formation of a weak minority government in the neighbouring former Soviet republic.
After months of negotiations, the Liberal Democratic Party, PLDM, and the Democratic Party, PDM, agreed late on January 23 to form a minority government in Moldova.